Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer

Inter- and intra-tumour heterogeneity is caused by genetic and non-genetic factors, leading to severe clinical implications. High-throughput sequencing technologies provide unprecedented tools to analyse DNA and RNA in single cells and explore both genetic heterogeneity and phenotypic variation betw...

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Detalles Bibliográficos
Autores principales: Fasterius, Erik, Uhlén, Mathias, Al-Khalili Szigyarto, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606766/
https://www.ncbi.nlm.nih.gov/pubmed/31267007
http://dx.doi.org/10.1038/s41598-019-45934-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606766/
https://www.ncbi.nlm.nih.gov/pubmed/31267007
http://dx.doi.org/10.1038/s41598-019-45934-1

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