Efficient Expression of HIV in Immunocompetent Mouse Brain Reveals a Novel Nonneurotoxic Viral Function in Hippocampal Synaptodendritic Injury and Memory Impairment

HIV causes neurodegeneration and dementia in AIDS patients, but its function in milder cognitive impairments in virologically suppressed patients on antiretroviral therapy is unknown. Such patients are immunocompetent, have low peripheral and brain HIV burdens, and show minimal brain neuropathology....

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Detalles Bibliográficos
Autores principales: Kelschenbach, Jennifer, He, Hongxia, Kim, Boe-Hyun, Borjabad, Alejandra, Gu, Chao-Jiang, Chao, Wei, Do, Meilan, Sharer, Leroy R., Zhang, Hong, Arancio, Ottavio, Potash, Mary Jane, Volsky, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606797/
https://www.ncbi.nlm.nih.gov/pubmed/31266862
http://dx.doi.org/10.1128/mBio.00591-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606797/
https://www.ncbi.nlm.nih.gov/pubmed/31266862
http://dx.doi.org/10.1128/mBio.00591-19

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