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The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC

The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which modulates many aspects of cell physiology, including r...

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Detalles Bibliográficos
Autores principales: Kraemer, James A., Sanderlin, Allen G., Laub, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606810/
https://www.ncbi.nlm.nih.gov/pubmed/31266875
http://dx.doi.org/10.1128/mBio.01330-19