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Increased error-free DNA repair gene expression through reprogramming in human iPS cells()

INTRODUCTION: Many studies have reported that human-induced pluripotent stem (hiPS)/embryonic stem (hES) cells have an exceptional ability to repair damaged DNA. Moreover, unlike differentiated cells, hES cells have features and mechanisms such as apoptosis-prone mitochondria, which prevent any chan...

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Detalles Bibliográficos
Autor principal: Yoshimura, Yasuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606834/
https://www.ncbi.nlm.nih.gov/pubmed/31304203
http://dx.doi.org/10.1016/j.reth.2019.06.003