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Salbutamol modifies the neuromuscular junction in a mouse model of ColQ myasthenic syndrome

The β-adrenergic agonists salbutamol and ephedrine have proven to be effective as therapies for human disorders of the neuromuscular junction, in particular many subsets of congenital myasthenic syndromes. However, the mechanisms underlying this clinical benefit are unknown and improved understandin...

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Detalles Bibliográficos
Autores principales: McMacken, Grace M, Spendiff, Sally, Whittaker, Roger G, O’Connor, Emily, Howarth, Rachel M, Boczonadi, Veronika, Horvath, Rita, Slater, Clarke R, Lochmüller, Hanns
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606850/
https://www.ncbi.nlm.nih.gov/pubmed/31220253
http://dx.doi.org/10.1093/hmg/ddz059