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A Novel Regulated Hybrid Promoter That Permits Autoinduction of Heterologous Protein Expression in Kluyveromyces lactis

The yeast Kluyveromyces lactis has been a successful host for the production of heterologous proteins for over 30 years. Currently, the galactose-/lactose-inducible and glucose-repressible LAC4 promoter (P(LAC4)) is the most widely used promoter to drive recombinant protein expression in K. lactis....

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Detalles Bibliográficos
Autores principales: Sakhtah, Hassan, Behler, Juliane, Ali-Reynolds, Alana, Causey, Thomas B., Vainauskas, Saulius, Taron, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606884/
https://www.ncbi.nlm.nih.gov/pubmed/31053583
http://dx.doi.org/10.1128/AEM.00542-19