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Pathway-based biomarker identification with crosstalk analysis for robust prognosis prediction in hepatocellular carcinoma

BACKGROUND: Although many prognostic single-gene (SG) lists have been identified in cancer research, application of these features is hampered due to poor robustness and performance on independent datasets. Pathway-based approaches have thus emerged which embed biological knowledge to yield reproduc...

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Detalles Bibliográficos
Autores principales: Fa, Botao, Luo, Chengwen, Tang, Zhou, Yan, Yuting, Zhang, Yue, Yu, Zhangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606892/
https://www.ncbi.nlm.nih.gov/pubmed/31101593
http://dx.doi.org/10.1016/j.ebiom.2019.05.010