MicroRNA-221 Is Cardioprotective and Anti-fibrotic in a Rat Model of Myocardial Infarction

Reduced myocardial miR-221 expression is associated with severe cardiac fibrosis in heart failure patients. We aimed to demonstrate its mechanisms in cardioprotection and remodeling following myocardial infarction (MI). Using in vitro hypoxia and reoxygenation (H/R) of H9c2 and rat cardiac fibroblas...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Richards, Arthur Mark, Wang, Peipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606926/
https://www.ncbi.nlm.nih.gov/pubmed/31261033
http://dx.doi.org/10.1016/j.omtn.2019.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606926/
https://www.ncbi.nlm.nih.gov/pubmed/31261033
http://dx.doi.org/10.1016/j.omtn.2019.05.018

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