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Immunomodulatory Effects of Colistin on Macrophages in Rats by Activating the p38/MAPK Pathway

Objectives: Colistin has been identified in a Caenorhabditis elegans chemical screening as an immunostimulatory agent that activates the conserved p38/PMK-1 pathway and provides protection against pathogens. Here we aimed to extend those findings to a mammalian model and evaluate the immunomodulator...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Shao, Weili, Niu, Hui, Yang, Tianli, Wang, Yuning, Cai, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606943/
https://www.ncbi.nlm.nih.gov/pubmed/31297059
http://dx.doi.org/10.3389/fphar.2019.00729