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Hyper-methylation of AVPR1A and PKCΒ gene associated with insensitivity to arginine vasopressin in human pre-eclamptic placental vasculature

BACKGROUND: Pre-eclampsia is a leading cause of maternal mortality and morbidity. Although the exact mechanisms that cause pre-eclampsia remain unclear, it is undeniable that abnormal placental function and circulation are a center for initiation pre-eclampsia. As a potent vasoconstrictor, arginine...

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Detalles Bibliográficos
Autores principales: Gao, Qinqin, Li, Huan, Ding, Hongmei, Fan, Xiaorong, Xu, Ting, Tang, Jiaqi, Liu, Yanping, Chen, Xueyi, Zhou, Xiuwen, Tao, Jianying, Xu, Zhice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606951/
https://www.ncbi.nlm.nih.gov/pubmed/31175056
http://dx.doi.org/10.1016/j.ebiom.2019.05.056