Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome

BACKGROUND: Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Women with PCOS exhibit elevated cerebrospinal fluid GABA levels and preclinical models of PCOS...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Mauro S.B., Desroziers, Elodie, Hessler, Sabine, Prescott, Melanie, Coyle, Chris, Herbison, Allan E., Campbell, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606966/
https://www.ncbi.nlm.nih.gov/pubmed/31178425
http://dx.doi.org/10.1016/j.ebiom.2019.05.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606966/
https://www.ncbi.nlm.nih.gov/pubmed/31178425
http://dx.doi.org/10.1016/j.ebiom.2019.05.065

Ejemplares similares