Lentivirus-mediated RNA interference targeting programmed death receptor ligand 1 increases the immunologic anti-tumor effect of dendritic cell vaccination against pancreatic cancer in SCID-hu mice

Programmed death receptor ligand 1 (PD-L1), which belongs to the B7 family, is overexpressed in a variety of human cancer types and serves a crucial role in immune escape by malignant cells. Programmed death receptor 1 (PD-1) is a specific PD-L1 receptor. PD-1/PD-L1 signaling inhibits the antitumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jin, Sun, Mingbing, Zhu, Xinguo, Zhao, Hua, Mao, Deli, Zhang, Zhe, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607057/
https://www.ncbi.nlm.nih.gov/pubmed/31423221
http://dx.doi.org/10.3892/ol.2019.10426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607057/
https://www.ncbi.nlm.nih.gov/pubmed/31423221
http://dx.doi.org/10.3892/ol.2019.10426

Ejemplares similares