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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males
PURPOSE: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the zona pellucida. Synthesis of human anti-PCSK4 might be important for novel male immunocontraception....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Urological Association
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607073/ https://www.ncbi.nlm.nih.gov/pubmed/31294140 http://dx.doi.org/10.4111/icu.2019.60.4.303 |