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A transcriptomic model to predict increase in fibrous cap thickness in response to high-dose statin treatment: Validation by serial intracoronary OCT imaging

BACKGROUND: Fibrous cap thickness (FCT), best measured by intravascular optical coherence tomography (OCT), is the most important determinant of plaque rupture in the coronary arteries. Statin treatment increases FCT and thus reduces the likelihood of acute coronary events. However, substantial stat...

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Detalles Bibliográficos
Autores principales: Johnson, Kipp W., Glicksberg, Benjamin S., Shameer, Khader, Vengrenyuk, Yuliya, Krittanawong, Chayakrit, Russak, Adam J., Sharma, Samin K., Narula, Jagat N., Dudley, Joel T., Kini, Annapoorna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607084/
https://www.ncbi.nlm.nih.gov/pubmed/31126891
http://dx.doi.org/10.1016/j.ebiom.2019.05.007