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Performance of Pyridylthiourea‐Polyethylenimine Polyplex for siRNA‐Mediated Liver Cancer Therapy in Cell Monolayer, Spheroid, and Tumor Xenograft Models

Medical application of siRNAs relies on methods for delivering nucleic acids into the cytosol. Synthetic carriers, which assemble with nucleic acids into delivery systems, show promises for cancer therapy but efficiency remains to be improved. In here, the effectiveness of pyridylthiourea‐polyethyle...

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Detalles Bibliográficos
Autores principales: Gossart, Jean Baptiste, Pascal, Etienne, Meyer, Florent, Heuillard, Emilie, Gonçalves, Mathieu, Gossé, Francine, Robinet, Eric, Frisch, Benoît, Seguin, Cendrine, Zuber, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607116/
https://www.ncbi.nlm.nih.gov/pubmed/31565271
http://dx.doi.org/10.1002/gch2.201700013