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Sustained corticosterone rise in the prefrontal cortex is a key factor for chronic stress-induced working memory deficits in mice

Exposure to prolonged, unpredictable stress leads to glucocorticoids-mediated long-lasting neuroendocrine abnormalities associated with emotional and cognitive impairments. Excessive levels of serum glucocorticoids (cortisol in humans, corticosterone in rodents) contribute notably to deficits in wor...

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Detalles Bibliográficos
Autores principales: Dominguez, Gaelle, Henkous, Nadia, Prevot, Thomas, David, Vincent, Guillou, Jean-Louis, Belzung, Catherine, Mons, Nicole, Béracochéa, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607320/
https://www.ncbi.nlm.nih.gov/pubmed/31309134
http://dx.doi.org/10.1016/j.ynstr.2019.100161