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Sustained corticosterone rise in the prefrontal cortex is a key factor for chronic stress-induced working memory deficits in mice
Exposure to prolonged, unpredictable stress leads to glucocorticoids-mediated long-lasting neuroendocrine abnormalities associated with emotional and cognitive impairments. Excessive levels of serum glucocorticoids (cortisol in humans, corticosterone in rodents) contribute notably to deficits in wor...
Autores principales: | Dominguez, Gaelle, Henkous, Nadia, Prevot, Thomas, David, Vincent, Guillou, Jean-Louis, Belzung, Catherine, Mons, Nicole, Béracochéa, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607320/ https://www.ncbi.nlm.nih.gov/pubmed/31309134 http://dx.doi.org/10.1016/j.ynstr.2019.100161 |
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