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Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells
Prions of lower eukaryotes are self-templating protein aggregates that replicate by converting homotypic proteins into stable, tightly packed beta-sheet–rich protein assemblies. Propagation is mediated by prion domains, low-complexity regions enriched in polar and devoid of charged amino acid residu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607448/ https://www.ncbi.nlm.nih.gov/pubmed/31266883 http://dx.doi.org/10.26508/lsa.201800280 |