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Adrenomedullin in heart failure: pathophysiology and therapeutic application

Adrenomedullin (ADM) is a peptide hormone first discovered in 1993 in pheochromocytoma. It is synthesized by endothelial and vascular smooth muscle cells and diffuses freely between blood and interstitium. Excretion of ADM is stimulated by volume overload to maintain endothelial barrier function. Di...

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Detalles Bibliográficos
Autores principales: Voors, Adriaan A., Kremer, Daan, Geven, Christopher, ter Maaten, Jozine M., Struck, Joachim, Bergmann, Andreas, Pickkers, Peter, Metra, Marco, Mebazaa, Alexandre, Düngen, Hans‐Dirk, Butler, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607488/
https://www.ncbi.nlm.nih.gov/pubmed/30592365
http://dx.doi.org/10.1002/ejhf.1366