CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways

BACKGROUND: Recent evidence has shown that C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in acute lung injury (ALI). Macrophages are key factors in the pathogenesis of ALI. The aim of this study was to investigate the role of CXCR4 in macrophages after lipopolysaccharide (LPS) stimula...

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Detalles Bibliográficos
Autores principales: Tian, Xue, Xie, Guogang, Xiao, Hui, Ding, Fengming, Bao, Wuping, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607528/
https://www.ncbi.nlm.nih.gov/pubmed/31304005
http://dx.doi.org/10.1186/s13578-019-0315-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607528/
https://www.ncbi.nlm.nih.gov/pubmed/31304005
http://dx.doi.org/10.1186/s13578-019-0315-x

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