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Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA

The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is gaining in importance in the fields of regenerative medicine, tissue engineering, and disease modeling. Patient-specific iPSCs have as an unlimited cell source a tremendous potential for generating various types of aut...

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Detalles Bibliográficos
Autores principales: Steinle, Heidrun, Weber, Marbod, Behring, Andreas, Mau-Holzmann, Ulrike, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607707/
https://www.ncbi.nlm.nih.gov/pubmed/31320906
http://dx.doi.org/10.1155/2019/7641767