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Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells

PURPOSE: Phosphatidylinositol-3-phosphate (PI(3)P), and Vps34, the type III phosphatidylinositol 3-kinase primarily responsible for its production, are important for function and survival of sensory neurons, where they have key roles in membrane processing events, such as autophagy, endosome process...

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Detalles Bibliográficos
Autores principales: He, Feng, Nichols, Ralph M., Kailasam, Lavanya, Wensel, Theodore G., Agosto, Melina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607926/
https://www.ncbi.nlm.nih.gov/pubmed/31260037
http://dx.doi.org/10.1167/iovs.19-26586