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In vitro and in vivo effect of hyaluronic acid modified, doxorubicin and gallic acid co-delivered lipid-polymeric hybrid nano-system for leukemia therapy

Objective: To investigate the hyaluronic acid (HA) modified, doxorubicin (DOX) and gallic acid (GA) co-delivered lipid-polymeric hybrid nano-system for leukemia therapy. Methods: We produced a kind of lipid-polymer hybrid nanoparticle (LPHN) with a core-shell structure in which DOX and GA were co-lo...

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Detalles Bibliográficos
Autores principales: Shao, Yanping, Luo, Wenda, Guo, Qunyi, Li, Xiaohong, Zhang, Qianqian, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607984/
https://www.ncbi.nlm.nih.gov/pubmed/31388296
http://dx.doi.org/10.2147/DDDT.S202818