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Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2

We describe two cases of hypertension and hypokalemia due to mineralocorticoid excess caused by posaconazole treatment of coccidioidomycosis and rhinocerebral mucormycosis infections, respectively. Clinical laboratory evaluations, including a comprehensive analysis of blood and urine steroid profile...

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Detalles Bibliográficos
Autores principales: Thompson, George R, Beck, Katharina R, Patt, Melanie, Kratschmar, Denise V, Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608555/
https://www.ncbi.nlm.nih.gov/pubmed/31286100
http://dx.doi.org/10.1210/js.2019-00189