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Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy

HIV-infected individuals are at high risk of tuberculosis disease and those with prior tuberculosis episodes are at even higher risk of disease recurrence. A non-sputum biomarker that identifies individuals at highest tuberculosis risk would allow targeted microbiological testing and appropriate tre...

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Detalles Bibliográficos
Autores principales: Darboe, Fatoumatta, Mbandi, Stanley Kimbung, Naidoo, Kogieleum, Yende-Zuma, Nonhlanhla, Lewis, Lara, Thompson, Ethan G., Duffy, Fergal J., Fisher, Michelle, Filander, Elizabeth, van Rooyen, Michele, Bilek, Nicole, Mabwe, Simbarashe, McKinnon, Lyle R., Chegou, Novel, Loxton, Andre, Walzl, Gerhard, Tromp, Gerard, Padayatchi, Nesri, Govender, Dhineshree, Hatherill, Mark, Karim, Salim Abdool, Zak, Daniel E., Penn-Nicholson, Adam, Scriba, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608601/
https://www.ncbi.nlm.nih.gov/pubmed/31297103
http://dx.doi.org/10.3389/fmicb.2019.01441