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Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography

Copper-containing nitrite reductases (CuNiRs) that convert NO(2) (−) to NO via a Cu(CAT)–His–Cys–Cu(ET) proton-coupled redox system are of central importance in nitrogen-based energy metabolism. These metalloenzymes, like all redox enzymes, are very susceptible to radiation damage from the intense s...

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Detalles Bibliográficos
Autores principales: Halsted, Thomas P., Yamashita, Keitaro, Gopalasingam, Chai C., Shenoy, Rajesh T., Hirata, Kunio, Ago, Hideo, Ueno, Go, Blakeley, Matthew P., Eady, Robert R., Antonyuk, Svetlana V., Yamamoto, Masaki, Hasnain, S. Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608623/
https://www.ncbi.nlm.nih.gov/pubmed/31316819
http://dx.doi.org/10.1107/S2052252519008285