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Catalytically important damage-free structures of a copper nitrite reductase obtained by femtosecond X-ray laser and room-temperature neutron crystallography
Copper-containing nitrite reductases (CuNiRs) that convert NO(2) (−) to NO via a Cu(CAT)–His–Cys–Cu(ET) proton-coupled redox system are of central importance in nitrogen-based energy metabolism. These metalloenzymes, like all redox enzymes, are very susceptible to radiation damage from the intense s...
Autores principales: | Halsted, Thomas P., Yamashita, Keitaro, Gopalasingam, Chai C., Shenoy, Rajesh T., Hirata, Kunio, Ago, Hideo, Ueno, Go, Blakeley, Matthew P., Eady, Robert R., Antonyuk, Svetlana V., Yamamoto, Masaki, Hasnain, S. Samar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608623/ https://www.ncbi.nlm.nih.gov/pubmed/31316819 http://dx.doi.org/10.1107/S2052252519008285 |
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