Cargando…
Plasticity enhancement in pharmaceutical drugs by water of crystallization: unusual slip planes
Khandavilli et al. [(2019), IUCrJ, 6, 630–634] show the superior plasticity in hydrates of the pharmaceutical drugs, pregabalin and gabapetin, compared with their anhydrous forms. The water in the structure is believed to act as a lubricating agent in the packing of hydrates, thus facilitating slipp...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608643/ https://www.ncbi.nlm.nih.gov/pubmed/31316794 http://dx.doi.org/10.1107/S205225251900890X |