Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM) has been intensely studied as a chronic inflammatory disease until recent observation...

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Detalles Bibliográficos
Autores principales: Ayyappan, Janeesh Plakkal, lizardo, Kezia, Wang, Sean, Yurkow, Edward, Nagajyothi, Jyothi F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609105/
https://www.ncbi.nlm.nih.gov/pubmed/30879276
http://dx.doi.org/10.4062/biomolther.2018.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609105/
https://www.ncbi.nlm.nih.gov/pubmed/30879276
http://dx.doi.org/10.4062/biomolther.2018.193

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