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Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model
Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM) has been intensely studied as a chronic inflammatory disease until recent observation...
Autores principales: | Ayyappan, Janeesh Plakkal, lizardo, Kezia, Wang, Sean, Yurkow, Edward, Nagajyothi, Jyothi F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609105/ https://www.ncbi.nlm.nih.gov/pubmed/30879276 http://dx.doi.org/10.4062/biomolther.2018.193 |
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