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7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells

Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine (OHDA)-induced neurotoxicity are not well understood....

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Detalles Bibliográficos
Autores principales: Ko, Yong-Hyun, Kim, Seon-Kyung, Kwon, Seung-Hwan, Seo, Jee-Yeon, Lee, Bo-Ram, Kim, Young-Jung, Hur, Kwang-Hyun, Kim, Sun Yeou, Lee, Seok-Yong, Jang, Choon-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609108/
https://www.ncbi.nlm.nih.gov/pubmed/30866601
http://dx.doi.org/10.4062/biomolther.2018.211