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Generation and Selection of a Panel of Pan-Filovirus Single-Chain Antibodies using Cell-Free Ribosome Display

Filoviruses, which include ebolaviruses and marburgvirus, can cause outbreaks of highly lethal hemorrhagic fever. This disease causes significant morbidity and mortality in humans and non-human primates, with human fatality rates reaching 90% during some outbreaks. Currently, there is lack of licens...

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Detalles Bibliográficos
Autores principales: Kunamneni, Adinarayana, Clarke, Elizabeth C., Ye, Chunyan, Bradfute, Steven B., Durvasula, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609206/
https://www.ncbi.nlm.nih.gov/pubmed/31074409
http://dx.doi.org/10.4269/ajtmh.18-0658