Transcriptional suppression of the miR-15/16 family by c-Myc in malignant pleural mesothelioma

MicroRNA downregulation is frequent in malignant pleural mesothelioma (MPM), but the mechanisms responsible for loss of miR-15/16 and miR-193a are yet to be elucidated and were investigated in this study. Copy Number Variation (CNV) of microRNA-coding genes was analyzed in MPM cells by digital dropl...

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Detalles Bibliográficos
Autores principales: Williams, Marissa, Cheng, Yuen Yee, Kirschner, Michaela B., Sarun, Kadir H., Schelch, Karin, Winata, Patrick, McCaughan, Brian, Kao, Steven, Van Zandwijk, Nico, Reid, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609241/
https://www.ncbi.nlm.nih.gov/pubmed/31289611
http://dx.doi.org/10.18632/oncotarget.27010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609241/
https://www.ncbi.nlm.nih.gov/pubmed/31289611
http://dx.doi.org/10.18632/oncotarget.27010

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