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GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer

Whole exome sequencing (WES) recently identified frequent mutations in the genes of GPCR-mediated PI3K pathway (LPAR4, PIK3CA, and PTEN) in a Chinese population with papillary thyroid cancers (PTCs). The study found LPAR4 mutations as novel gene mutations in adult population with differentiated thyr...

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Detalles Bibliográficos
Autores principales: Murugan, Avaniyapuram Kannan, Qasem, Ebtesam, Al-Hindi, Hindi, Alzahrani, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609254/
https://www.ncbi.nlm.nih.gov/pubmed/31289610
http://dx.doi.org/10.18632/oncotarget.26993