Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches

The study of tumorigenic rewiring of metabolic flux is at the heart of cancer metabolic research. Here, we review two widely used computational flux inference approaches: isotope tracing coupled with Metabolic Flux Analysis (13C-MFA) and COnstraint-Based Reconstruction and Analysis (COBRA). We descr...

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Detalles Bibliográficos
Autores principales: Lagziel, Shoval, Lee, Won Dong, Shlomi, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609376/
https://www.ncbi.nlm.nih.gov/pubmed/31272436
http://dx.doi.org/10.1186/s12915-019-0669-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609376/
https://www.ncbi.nlm.nih.gov/pubmed/31272436
http://dx.doi.org/10.1186/s12915-019-0669-x

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