High-throughput identification of human SNPs affecting regulatory element activity

Most of the millions of single-nucleotide polymorphisms (SNPs) in the human genome are non-coding, and many overlap with putative regulatory elements. Genome-wide association studies (GWAS) have linked many of these SNPs to human traits or to gene expression levels, but rarely with sufficient resolu...

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Detalles Bibliográficos
Autores principales: van Arensbergen, Joris, Pagie, Ludo, FitzPatrick, Vincent D, de Haas, Marcel, Baltissen, Marijke P, Comoglio, Federico, van der Weide, Robin H, Teunissen, Hans, Võsa, Urmo, Franke, Lude, de Wit, Elzo, Vermeulen, Michiel, Bussemaker, Harmen J, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609452/
https://www.ncbi.nlm.nih.gov/pubmed/31253979
http://dx.doi.org/10.1038/s41588-019-0455-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609452/
https://www.ncbi.nlm.nih.gov/pubmed/31253979
http://dx.doi.org/10.1038/s41588-019-0455-2

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