DISTINCTIVE REQUIREMENT OF PKCε IN THE CONTROL OF Rho GTPases IN EPITHELIAL AND MESENCHYMALLY-TRANSFORMED LUNG CANCER CELLS

Diacylglycerol (DAG)/phorbol ester-regulated protein kinase C (PKC) isozymes have been widely linked to tumor promotion and the development of a metastatic phenotype. PKCε, an oncogenic member of the PKC family, is abnormally overexpressed in lung cancer and other cancer types. This kinase plays sig...

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Detalles Bibliográficos
Autores principales: Casado-Medrano, Victoria, Barrio-Real, Laura, Wang, Anita, Cooke, Mariana, Lopez-Haber, Cynthia, Kazanietz, Marcelo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609469/
https://www.ncbi.nlm.nih.gov/pubmed/30923343
http://dx.doi.org/10.1038/s41388-019-0796-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609469/
https://www.ncbi.nlm.nih.gov/pubmed/30923343
http://dx.doi.org/10.1038/s41388-019-0796-4

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