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DISTINCTIVE REQUIREMENT OF PKCε IN THE CONTROL OF Rho GTPases IN EPITHELIAL AND MESENCHYMALLY-TRANSFORMED LUNG CANCER CELLS

Diacylglycerol (DAG)/phorbol ester-regulated protein kinase C (PKC) isozymes have been widely linked to tumor promotion and the development of a metastatic phenotype. PKCε, an oncogenic member of the PKC family, is abnormally overexpressed in lung cancer and other cancer types. This kinase plays sig...

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Detalles Bibliográficos
Autores principales:	Casado-Medrano, Victoria, Barrio-Real, Laura, Wang, Anita, Cooke, Mariana, Lopez-Haber, Cynthia, Kazanietz, Marcelo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609469/ https://www.ncbi.nlm.nih.gov/pubmed/30923343 http://dx.doi.org/10.1038/s41388-019-0796-4

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