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Association Between TDP-43 and Mitochondria in Inclusion Body Myositis

Inclusion body myositis (IBM) is the most common cause of primary myopathy in individuals ages 50 years and over, and is pathologically characterized by protein aggregates of p62 and mislocalized cytoplasmic TDP-43 as well as mitochondrial abnormalities in affected muscle fibers. Our recent studies...

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Detalles Bibliográficos
Autores principales: Huntley, Mikayla L., Gao, Ju, Termsarasab, Pichet, Wang, Luwen, Zeng, Sophia, Thammongkolchai, Thananan, Liu, Ying, Cohen, Mark L., Wang, Xinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609472/
https://www.ncbi.nlm.nih.gov/pubmed/30742062
http://dx.doi.org/10.1038/s41374-019-0233-x