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Structural basis of tubulin detyrosination by vasohibins

Microtubules are regulated by posttranslational modifications (PTMs) of tubulin. The ligation and cleavage of the C-terminal tyrosine of α tubulin impact microtubule functions during mitosis, cardiomyocyte contraction, and neuronal processes. Tubulin tyrosination and detyrosination are mediated by t...

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Detalles Bibliográficos
Autores principales: Li, Faxiang, Hu, Yingjie, Qi, Shutao, Luo, Xuelian, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609488/
https://www.ncbi.nlm.nih.gov/pubmed/31235910
http://dx.doi.org/10.1038/s41594-019-0242-x