Enterohepatic circulation of glucuronide metabolites of drugs in dog

The enterohepatic circulation (EHC) of drugs is often the result of the direct glucuronidation, excretion of the metabolite into bile, followed by hydrolysis to the aglycone by the gut microbiome and finally reabsorption of drug into the systemic circulation. The aim of present study to identify key...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Cassidy, Kenneth C., Hudson, Loyd, Mohutsky, Michael A., Sawada, Geri A., Hao, Junliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609541/
https://www.ncbi.nlm.nih.gov/pubmed/31333846
http://dx.doi.org/10.1002/prp2.502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609541/
https://www.ncbi.nlm.nih.gov/pubmed/31333846
http://dx.doi.org/10.1002/prp2.502

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