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Enterohepatic circulation of glucuronide metabolites of drugs in dog
The enterohepatic circulation (EHC) of drugs is often the result of the direct glucuronidation, excretion of the metabolite into bile, followed by hydrolysis to the aglycone by the gut microbiome and finally reabsorption of drug into the systemic circulation. The aim of present study to identify key...
Autores principales: | Zhou, Xin, Cassidy, Kenneth C., Hudson, Loyd, Mohutsky, Michael A., Sawada, Geri A., Hao, Junliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609541/ https://www.ncbi.nlm.nih.gov/pubmed/31333846 http://dx.doi.org/10.1002/prp2.502 |
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