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Carboxypeptidase Y activity and maintenance is modulated by a large helical structure

Yeast carboxypeptidase Y (CPY) is a serine protease with broad substrate specificity. Structurally, CPY belongs to the α/β hydrolase fold family and contains characteristic large helices, termed the V‐shape helix, above the active site cavity. Four intramolecular disulfide bonds are located in and a...

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Detalles Bibliográficos
Autores principales: Makino, Mai, Sahara, Takehiko, Morita, Naoki, Ueno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609556/
https://www.ncbi.nlm.nih.gov/pubmed/31173671
http://dx.doi.org/10.1002/2211-5463.12686