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Allicin alleviates lead-induced hematopoietic stem cell aging by up-regulating PKM2

Hematopoietic stem cells (HSCs) aging is associated with hematopoietic dysfunction and diseases. Our previous study showed that lead exposure induced a functional decline in HSCs. Allicin, a chemical extracted from the garlic (Allium sativum L.), has been reported to have antioxidative and anti-infl...

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Detalles Bibliográficos
Autores principales: Cai, Shi-zhong, Zhao, Li-na, Liu, Jun, Ji, Yi-ting, Shi, Xiao-yan, Ma, Zhou-rui, Lv, Xiao-hua, Chen, Ke, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609558/
https://www.ncbi.nlm.nih.gov/pubmed/31213573
http://dx.doi.org/10.1042/BSR20190243