Cargando…

Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis

Background: Glucocorticoid resistance—reduced function of the glucocorticoid receptor (GR)—is seen in many depressed patients. It is argued that this resistance to glucocorticoids leads to failure of normal feedback regulation on the immune system. High levels of pro-inflammatory cytokines result. P...

Descripción completa

Detalles Bibliográficos
Autores principales: Perrin, Andrew J., Horowitz, Mark A., Roelofs, Jacob, Zunszain, Patricia A., Pariante, Carmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609575/
https://www.ncbi.nlm.nih.gov/pubmed/31316402
http://dx.doi.org/10.3389/fpsyt.2019.00423