Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Type 2 diabetes (T2D) mellitus is a complex metabolic disease commonly caused by insulin resistance in several tissues. We performed a matched two-dimensional metabolic screening in tissue samples from 43 multi-organ donors. The intra-individual analysis was assessed across five key metabolic tissue...

Descripción completa

Detalles Bibliográficos
Autores principales: Diamanti, Klev, Cavalli, Marco, Pan, Gang, Pereira, Maria J., Kumar, Chanchal, Skrtic, Stanko, Grabherr, Manfred, Risérus, Ulf, Eriksson, Jan W., Komorowski, Jan, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609645/
https://www.ncbi.nlm.nih.gov/pubmed/31273253
http://dx.doi.org/10.1038/s41598-019-45906-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609645/
https://www.ncbi.nlm.nih.gov/pubmed/31273253
http://dx.doi.org/10.1038/s41598-019-45906-5

Ejemplares similares