Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification

Elastin plays an important role in maintaining blood vessel integrity. Proteolytic degradation of elastin in the vascular system promotes the development of atherosclerosis, including blood vessel calcification. Cysteine cathepsins have been implicated in this process, however, their role in disease...

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Detalles Bibliográficos
Autores principales: Andrault, Pierre-Marie, Panwar, Preety, Mackenzie, Neil C. W., Brömme, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609650/
https://www.ncbi.nlm.nih.gov/pubmed/31273243
http://dx.doi.org/10.1038/s41598-019-45918-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609650/
https://www.ncbi.nlm.nih.gov/pubmed/31273243
http://dx.doi.org/10.1038/s41598-019-45918-1

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