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IFITM3 promotes bone metastasis of prostate cancer cells by mediating activation of the TGF-β signaling pathway
Advanced-stage prostate cancer (PCa) is often diagnosed with bone metastasis, for which there are limited therapies. Transforming growth factor β (TGF-β) is known to induce epithelial–mesenchymal transition (EMT), and abundance of TGF-β in the bone matrix is one of the important growth factors contr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609682/ https://www.ncbi.nlm.nih.gov/pubmed/31273201 http://dx.doi.org/10.1038/s41419-019-1750-7 |