Activation of The Phosphatidylcholine to Lysophosphatidylcholine Pathway Is Associated with Osteoarthritis Knee Cartilage Volume Loss Over Time

To identify serum biomarker(s) for predicting knee cartilage volume loss over time, we studied 139 knee osteoarthritis (OA) patients from a previous 24-month clinical trial cohort. Targeted metabolomic profiling was performed on serum collected at baseline. The pairwise metabolite ratios as proxies...

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Detalles Bibliográficos
Autores principales: Zhai, Guangju, Pelletier, Jean-Pierre, Liu, Ming, Aitken, Dawn, Randell, Edward, Rahman, Proton, Jones, Graeme, Martel-Pelletier, Johanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609700/
https://www.ncbi.nlm.nih.gov/pubmed/31273319
http://dx.doi.org/10.1038/s41598-019-46185-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609700/
https://www.ncbi.nlm.nih.gov/pubmed/31273319
http://dx.doi.org/10.1038/s41598-019-46185-w

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