Facilitating the transmetalation step with aryl-zincates in nickel-catalyzed enantioselective arylation of secondary benzylic halides

Nickel-catalyzed asymmetric cross-coupling of secondary alkyl electrophiles with different nucleophiles represents a powerful strategy for the construction of chiral tertiary carbon centers. Yet, the use of aryl Grignard reagents or aryl zinc halides in many reactions typically resulted in low enant...

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Detalles Bibliográficos
Autores principales: Huang, Weichen, Hu, Mei, Wan, Xiaolong, Shen, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609707/
https://www.ncbi.nlm.nih.gov/pubmed/31273211
http://dx.doi.org/10.1038/s41467-019-10851-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609707/
https://www.ncbi.nlm.nih.gov/pubmed/31273211
http://dx.doi.org/10.1038/s41467-019-10851-4

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